NFE2 regulates transcription of multiple enzymes in the heme biosynthesis pathway
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چکیده
منابع مشابه
NFE2 regulates transcription of multiple enzymes in the heme biosynthesis pathway.
During erythroid differentiation, cooperative activities of erythroid transcription factors coordinate transcript levels of genes required for correct maturation. 1 These genes include the eight heme biosynthetic enzymes that are sequentially up-regulated to ensure augmented heme synthesis essential for the formation of hemoglobin. The transcription factor nuclear factor erythroid 2 (NFE2) play...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2014
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2014.106393